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This mechanism of action leads to several beneficial effects: Enhanced insulin secretion after meals Reduced production of glucagon, a hormone that elevates blood sugar Delayed stomach emptying, promoting prolonged satiety and decreased hunger Diminished food intake due to appetite suppression Together, these effects contribute to semaglutide’s remarkable ability to facilitate weight loss in individuals grappling with obesity or excess weight

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[DOI] [PMC free article] [PubMed] [Google Scholar] 29.Graaf Cd, Donnelly D, Wootten D, Lau J, Sexton PM, Miller LJ, et al