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The obesity drug semaglutide (Wegovy) conferred a significantly higher risk of ischemic optic neuropathy (ION) than any other GLP-1 agonist, including semaglutide for diabetes (Ozempic), an analysis of FDA data showed. Added
Common adverse effects include gastrointestinal symptoms (nausea, vomiting, diarrhoea, constipation), which typically improve over time
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In Hashimoto's patients already on thyroid replacement therapy, this mechanism could theoretically reduce medication efficacy
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