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“And when you're supporting estrogen and progesterone, you put those really important messengers back into the equation.” Used to treat a host of menopause-related concerns, such as hot flashes, poor sleep, vaginal dryness or discomfort, and for preventing bone loss, studies show that HRT may also reduce the change in body composition that occurs during menopause

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However, in patients with obesity, large amounts of epicardial fat cause mechanical inhibition, making it difficult for the LV to compensate for the expanded volume