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However, despite only differing by 2 of the 39 residues (Gly 2 , Glu 3 in Ex4, compared with Ser 2 , Asp 3 in exendin-3), Ex4 was found to have distinct pharmacological properties and does not act at VIP or secretin receptors

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this is largely true, but they all generally lack just one or two of them—and not the same ones