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GLP-1 RAs found to shrink heart muscle in mice and human cells owenhaskins Nov 21, 2024 3 min read Updated: Nov 22, 2024 Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) may be associated with shrinking the human heart and other muscles, according to a University of Alberta study
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Research has also implicated GLP-1R activation in the CNS with neuroprotective effects in Alzheimer’s disease models, but also suggests that neuropsychological symptoms such as depression can be exacerbated through GLP-1R activation
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