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Injection site reactions : Discomfort or pain at injection sites may limit physical activity Fatigue : Directly reported by some patients as an adverse event Decreased appetite : While therapeutically beneficial, excessive appetite suppression may lead to insufficient energy intake Serious adverse reactions requiring immediate medical attention include: Pancreatitis: Severe abdominal pain, sometimes radiating to the back, with or without vomiting Gallbladder problems: Pain in the right or middle upper abdomen, fever, jaundice Allergic reactions: Rash, itching, swelling of face/throat, severe dizziness Thyroid tumors: Lump or swelling in the neck, hoarseness, trouble swallowing or breathing Patients experiencing persistent or severe side effects should consult their healthcare provider