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Curious how a slow-moving lizard sparked one of the biggest pharmaceutical breakthroughs of our time? The blockbuster GLP-1 drugs behind today's diabetes and weight-loss treatments have an origin story few people know

Hinrichs GR, Hovind P, Asmar A

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A ROLE FOR GLP-1 IN THE PATHOPHYSIOLOGY OF CLINICAL OBESITY Genetics Genetic analyses in man suggest clinical obesity is associated with a lack of functional GLP-1 signalling that may contribute to the development of the obesity phenotype