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The relevant labeling language (paraphrased): Reduction of risk of sustained eGFR decline, kidney failure, and cardiovascular death In adults with type 2 diabetes mellitus and chronic kidney disease Dose: 1.0 mg weekly (the dose used in FLOW) The label is type 2 diabetes specific
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As described by the investigators, the observed association may be explained by several biologically plausible mechanisms rather than a confirmed causal pathway