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The alcohol and semaglutide interaction is also relevant here, since alcohol use affects liver enzymes independently and adds a layer of complexity to interpreting ALT and AST changes
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Del Prato S, Kahn SE, Pavo I, et al Tirzepatide versus insulin glargine in type 2 diabetes and increased cardiovascular risk (SURPASS‐4): a randomised, open‐label, parallel‐group, multicentre, phase 3 trial
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