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If allodynia were a pure GLP-1 class effect, one would expect it to appear with any GLP-1 agonist at sufficient doses

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Los mecanismos fisiológicos incluyen : adaptación metabólica con reducción del gasto energético en reposo, cambios en las hormonas intestinales (GLP-1, PYY, grelina), y dilatación gradual del reservorio gástrico que permite mayor ingesta calórica