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Because these treatments actively slow down your entire GI system, using the wrong over-the-counter options can make your symptoms significantly worse

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The array sensitivity analysis indicated that the two exposure groups would need to have at least a 15 percentage point imbalance in an unmeasured confounder with a confounder-outcome risk ratio of 3.5 or a 30 percentage point imbalance with a confounder-outcome risk ratio of 2.0 to bias our results by at least 25% (supplementary figure S3A)