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[20] Mechanism of action [edit] Exenatide binds to the intact human glucagon-like peptide-1 receptor (GLP-1R) in a similar way to the human peptide glucagon-like peptide-1 (GLP-1)

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Reduced contraction frequency means bile sits for longer in the gallbladder — a state called bile stasis — giving cholesterol crystals the time and conditions to coalesce into solid stones