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T2DM represents a significant public health burden, with an estimated prevalence of 38.1 million adults in the United States as of 2021 [5]
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These medications—including semaglutide (injectable Ozempic, oral Rybelsus, injectable Wegovy), dulaglutide (Trulicity), and liraglutide (Victoza, Saxenda)—mimic the action of endogenous GLP-1 while resisting degradation by the enzyme dipeptidyl peptidase-4 (DPP-4)
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