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Additionally, retatrutide demonstrated robust improvements in several key cardiometabolic markers 1 : Triglycerides: Reduced by 37% Non–high-density lipoprotein cholesterol: Reduced by 16.5% High-sensitivity C-reactive protein (hsCRP): Reduced by 51.2% Systolic blood pressure: Reduced by 9.3 mmHg Goldman highlighted the significance of the hsCRP reduction, noting that, “…systemic inflammation is a key driver of atherosclerotic cardiovascular disease and is increasingly recognized as a therapeutic target independent of traditional lipid lowering.” Background: The Foundation of TRIUMPH-1 The new data build upon the foundational TRIUMPH-1 results announced on May 21, 2026

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