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A study investigating the molecular mechanisms of GLP-1 acting within the PVN found that using a genetic strategy to block AMPA receptor trafficking following exendin-4 administration to the PVN resulted in a blunted reduction in food intake(Liu et al., 2017)
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One study presented at AAOS’ 2026 Annual Meeting found GLP-1s may help improve postoperative outcomes after certain orthopedic procedures
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