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The two medications were the only ones deemed not to be cost-effective for patients

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With regard to lipid metabolism, a 2008 meta-analysis of 14 randomized controlled trials reported that konjac glucomannan supplementation was associated with significant reductions in total cholesterol (≈ −19 mg/dL) and LDL-cholesterol (≈ −16 mg/dL) ( Sood et al