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Unlike FDA-approved drugs, compounded versions have not been proven to be safe, effective or consistently manufactured. https://www.kxan.com/news/compounded-glp-1-drugs -creating-concern-among-doctors-and-fda/?utm_medium=social&utm_source=facebook_KXAN_News

To address this critical issue, the past decade has witnessed a surge in cardiovascular outcome trials (CVOTs) focused on evaluating the cardiovascular safety and efficacy of various antidiabetic drugs

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According to the news release announcing its approval, orforglipron should be used alongside a reduced-calorie diet and increased physical activity