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What to submit: Completed appeal form (available on CVS Caremark member portal) Letter from prescriber explaining why denial was incorrect Supporting documentation: BMI measurements, lifestyle intervention logs, documentation of step therapy completion or contraindication, peer-reviewed studies supporting use Success rate: 24% of standard appeals result in approval (CVS Caremark 2025 data)

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Thermogenesis assays were performed in the home cage during the animal’s light phase at week 1 and week 11 in the preventive setting and at day 7 and 21 in the curative setting