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Design and Baseline Characteristics of the FLOW Trial of Semaglutide in Patients With Type 2 Diabetes and Chronic Kidney Disease If this sounds like déjà vu, that may be because Novo Nordisk previously implied that FLOW was positive on October 10 , 202 3 , when the trial was stopped early for efficacy (Figure 2)

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This potentially leads to limitations in GLP-1 receptor agonist use in patients who are unwilling or unable to administer these medications subcutaneously