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If a compounded vial has a 28-day BUD and your dosing schedule only uses 60% of the vial in that time, your effective cost per dose is nearly double the theoretical cost

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The key markers here are: Serum creatinine and estimated glomerular filtration rate (eGFR) — the standard measures of kidney filtration capacity Blood urea nitrogen (BUN) — a secondary marker that rises when the kidneys struggle Urine albumin-to-creatinine ratio (uACR) — especially relevant in patients with diabetes or hypertension, where early kidney damage often manifests as protein leaking into urine before eGFR declines From a dosing standpoint, most GLP-1 prescribing information does not require dose adjustment until eGFR falls significantly, but patients with an eGFR below 60 mL/min/1.73m² warrant more frequent monitoring and clinical discussion about hydration strategy.[4] Ask: "Based on my kidney function, are there any specific precautions I should follow, and when do we recheck these markers?" Question 4: Do I Need a Thyroid Panel, Given the Warnings on the Label