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The SURMOUNT-1 trial (Jastreboff et al., 2022, New England Journal of Medicine) showed tirzepatide produced mean weight loss of up to 20.9% of body weight over 72 weeks in adults with obesity

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Proc Nutr Soc 74(4):355–366 [DOI] [PubMed] [Google Scholar] 21.Wilding JPH, Batterham RL, Calanna S, Davies M, Van Gaal LF, Lingvay I et al (2021) Once-Weekly semaglutide in adults with overweight or obesity