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Finally, it’s important to note that making dietary changes to boost GLP-1 release is likely not comparable to the effectiveness of GLP-1 receptor agonist medications like semaglutide

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The use of prazosin, an α1-adrenergic receptor blocker, showed that the ability of GLP-1RAs to reduce TNF-α in plasma was disrupted, signifying the vital role of α1-adrenergic receptors in the anti-inflammatory action of GLP-1RAs

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