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Frontiers | GLP-1R as a potential link between diabetes and Alzheimer's disease
“Based on the significant unmet need in Alzheimer’s disease as well as a number of indicative data points, we felt we had a responsibility to explore semaglutide’s potential, despite a low likelihood of success,” Martin Holst Lange, chief scientific officer at Novo Nordisk said in a press release
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Secondly, elevated cAMP levels activate protein kinase A (PKA), which subsequently mediates the activation of AMP-activated protein kinase (AMPK)
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