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Glucose-induced membrane depolarization entails opening of voltage-dependent Ca 2+ (VDC) channels, and the resulting Ca 2+ influx then triggers vesicular exocytosis and secretion of GLP-1 into the circulation (Figure 3) [266]

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BCBSTX is a Division of Health Care Service Corporation (HCSC) (which operates Blue Cross and Blue Shield plans in Texas, Illinois, Montana, Oklahoma and New Mexico), the country's largest customer-owned health insurer