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In vivo and in vitro studies indicate that berberine upregulates phosphorylated AKT levels in the hippocampus of chronically restrained mice, in cardiac tissue of lipopolysaccharide (LPS)-induced septic mice, and in rotenone-treated SH-SY5Y cells [90,91,92]
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doi: 10.1097/FJC.0000000000000176