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Moreover, studies conducted on animal models have shown that enteroendocrine L-cells increase the secretion of GLP-1 in response to inflammatory cytokines (e.g., interleukin-6 (IL-6) and lipopolysaccharide (LPS) (38)) and ischaemic injury (39)

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Additionally, some users experience visible signs of rapid weight loss, such as a change in facial appearance (sometimes informally referred to as “Ozempic face”)