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JCI Insight - Hepatocyte-derived DPP4 regulates portal GLP-1 bioactivity, modulates glucose production, and when absent influences NAFLD progression
Thirdly, and perhaps most notably for weight management, GLP-1 slows gastric emptyingโmeaning food stays in the stomach longer, promoting feelings of fullness (though this effect may worsen symptoms in people with gastroparesis)
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