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Physiologic Role of GIP The physiologic role of GIP has been investigated over many decades, and a combination of human and mouse data, reinforced by the resistance of GIP receptor knockout (KO) mice to diet-induced obesity (DIO), resulted in GIP being regarded as the so-called obesity hormone (5,6)

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A SGLT2 Inhibitor Dapagliflozin Suppresses Prolonged Ventricular-Repolarization through Augmentation of Mitochondrial Function in Insulin-Resistant Metabolic Syndrome Rats