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Such observations raise safety concerns about GLP-1 RAs
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Expert Review of Endocrinology & Metabolism, 2025) The Fertility Paradox Worth Discussing With Your Provider For patients not actively trying to conceive, restored ovulation can be an unexpected and clinically significant side effect of treatment — meaning contraception planning should be part of the conversation when starting GLP-1 therapy for PCOS, not an afterthought
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