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Semaglutide may be unsuitable or require additional caution in patients who: • are pregnant, breastfeeding or trying to conceive • have a history of pancreatitis • have severe gastrointestinal disease • have delayed stomach emptying • have significant kidney or liver impairment • use insulin or medicines that can cause hypoglycaemia • have diabetic retinopathy • have an active or previous eating disorder • have experienced a serious allergic reaction to semaglutide • already use another GLP-1 or GIP/GLP-1 medicine • are due to undergo surgery, sedation or general anaesthesia These factors are not all automatic exclusions
