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수용체와 결합한 세마글루타이드 대표적으로 위고비의 주요 성분인 세마글루타이드는 GLP-1의 8번 단백질인 알라닌(Ala8)을 α-아미노이소부티르산으로 대체하여 GLP-1이 DDP-4 효소에 의해 분해되는 것을 방지합니다
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Retatrutide has Phase 3 safety data, but MOTS-c data is mostly from animals and one related analog trial