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Key points: • Leverage platform data from similar biologics • Eliminate redundant toxicology studies • Combine endpoints within the same study • Use in vitro and computational models earlier • Align with the 3Rs principle (Replacement, Reduction, Refinement) Important step toward more ethical and efficient ocular drug development
50-75
ML:3 ml
Sixty participants in group 1 withdrew after being exposed to treatment, with 162 completing the study
US$ 23.49
US$ 21.31
US$ 20.11
US$ 29.49
US$ 29.80
