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Furthermore, liraglutide has been shown to inhibit endoplasmic reticulum stress, as well as related apoptosis and inflammatory reactions are mediated through the cAMP/PKA/CREB pathway in BV2 cells that have been exposed to lipopolysaccharide (LPS) or tunicamycin (TM), a mouse-derived microglial cell line [111]
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Animal studies have demonstrated that GLP-1 receptors are present in the mesolimbic reward pathway, including the ventral tegmental area and nucleus accumbens—brain regions implicated in food reward and addictive behaviors
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