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In-Vitro Research
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Endoxifen may be tried as an adjunct treatment for acute mania, particularly when concurrent impulsivity or aggression is marked, and other treatment options are either not viable or exhausted.[253] Gender differences in the management of bipolar disorder Although the overall treatment principles remain broadly similar across both genders, certain distinctions in clinical presentations and special considerations are worth noting, as they can help individualize clinical care where relevant: Women tend to show a depressive-predominant polarity, more rapid cycling and mixed features, and higher rates of BD-II
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