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Inflammation and Oxidative Stress in Diabetic Kidney Disease: The Targets for SGLT2 Inhibitors and GLP-1 Receptor Agonists

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Type:Ebook (.epub)

To examine the requirement of the peptide hormone N-terminus for receptor activation, we fused full length or N-terminally truncated GLP-1 or EX4 peptide via a 15 amino acid linker (five copies of Gly-Ser-Ala [5xGSA]) to the N-terminus of GLP-1R (Figure 1b)