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Evaluating the True Cost of GLP-1 Coverage
24.2% after 14 hr, n=33
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In previous GLP-1- or exendin-P5-bound active structures 3,4 , the ECD shows a fully extended open conformation, whereas in the peptide 5-bound active-like structure 12 , the ECD is less extended since it makes fewer interactions with the truncated peptide 5
