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In studies of insulin secretion using the isolated perfused pancreas, Mojsov and Weir demonstrated that GLP-1(7-37) and not GLP-1(1-37) stimulated insulin secretion at concentrations as low as 50 pM (ref

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[PubMed] [Google Scholar] 5.Lund PK, Goodman RH, Montminy MR, Dee PC, Habener JF