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Option 2: keep both in the morning, in order If you’d rather keep levothyroxine in the morning, we recommend you take it second, after the Wegovy pill’s 30-minute window: Take the Wegovy pill as soon as you wake up, with a small sip of water Wait at least 30 minutes, with no food, drink, or other tablets Take your levothyroxine with water Wait a further 30 minutes or so before breakfast, tea, or coffee This approach maintains a gap between the two medications rather than taking them together