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In over-accumulated WAT, fatty acid by-products, mainly diacylglycerol (DAG), are metabolized through β-oxidation in the tricarboxylic acid (TCA) cycle, and under the DAG stimulation of PKC, the NADPH oxidase is directly activated to generate excess ROS [145]
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![Mechanism of action of GLP-1 [25]](https://www.researchgate.net/publication/256289222/figure/fig1/AS:614177232142337@1523442671231/Mechanism-of-action-of-GLP-1-25.png)
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