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Each macronutrient has the capacity to stimulate GLP-1 and GIP release, although the mechanisms underlying secretion differ, and fat and carbohydrate may be more potent stimuli than protein (8)

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Metabolic effects: For patients with type 2 diabetes, blood glucose levels typically begin rising as the medication's insulinotropic and glucagon-suppressing effects wane

GIP also stimulates insulin production and release from the pancreas