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currently setmelanotide is the only FDA-approved medication in this age group, specifically approved for Bardet–Biedl syndrome or monogenic obesity due to specific genetic mutations [16,17]
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Characterized by emotional disturbances, stress, guilt, and treatment avoidance, DD affected approximately 45% of patients worldwide-a prevalence underscoring its clinical significance [Reference Parsa, Aghamohammadi and Abazari57]