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Critical Safety Considerations: Thyroid Monitoring With GLP-1 Therapy Before starting semaglutide, anyone with hypothyroidism should have current thyroid function tests (TSH and free T4) confirming stable hormone replacement on their current levothyroxine dose

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Daniels's team investigated how GLP-1 drugs regulate thirst and drinking behavior using Brattleboro rats, a common animal model of a rare disorder called diabetes insipidus, which causes the animal to excessively urinate and subsequently drink water

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