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The standard protocol involves increasing the dose every four weeks, moving from 0.25 mg to 0.5 mg, then to 1 mg, and eventually up to 2.4 mg for maintenance
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In their study, four severely obese patients diagnosed with pathogenic heterozygous MC4R variants (2 adults and 2 adolescents) achieved a mean weight reduction of 5.9 kg following 16 weeks of liraglutide treatment, corresponding to a 5.8% reduction from their baseline body weight
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