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Many, including the supplement Konzier took, feature the plant-derived compound berberine, also called “nature’s Ozempic.” Some studies have found berberine can increase GLP-1 production in rats, and potentially drive moderate weight loss in humans, but researchers have called for more conclusive evidence
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Since both groups followed the same intensive lifestyle program, that gap is specifically what Contract added on top of diet and exercise— meaning Contrave provided nearly double the results of the lifestyle changes alone
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