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Its extended half-life profile is conferred by a C20 fatty acid conjugate enabling an extended characterized half-life in research models
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274 Donepezil is an acetylcholinesterase inhibitor that promotes the activation of AMPK and inhibits the activation of the NF-κB pathway by facilitating the expression of low-density lipoprotein receptor-associated protein 1, thereby reducing inflammation and intestinal epithelial apoptosis in the colon
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