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Tirzepatide's most common side effects are gastrointestinal: nausea, vomiting, constipation, and diarrhea, which typically diminish over 4–8 weeks

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Given that beneficial roles of GLP1 analogues for the prevention of CVD and kidney disease have been well established 80,102 , these drugs could be an ideal option for the treatment of patients with diabetes mellitus at such risk 103