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Last month, the European Medicines Agency recommended that product information for #semaglutide medicines— the active ingredient in #Ozempic, #Rybelsus, and #Wegovy — be updated to include non-arteritic anterior ischemic optic neuropathy or #
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Continuous infusion of exendin-4 over 28 days reduced monocyte adhesion to the endothelium, downregulated aortic mRNA expression of intercellular adhesion molecule-1 (ICAM-1), and suppressed atherogenesis in Apoe –/– mice on HFD without affecting LDL-cholesterol (LDL-C) levels (6)
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